Support:Documents:Manual:COMKAT Input Function

The input function toolbox starts with whole blood activity page. To see which page you are currently on look at the section of Steps which is present on the lower left hand side corner of the toolbox, where the current active page is highlighted. The toolbox starts by first defining the Whole blood acitivty followed by Metabolites (Ligand in plasma fraction) and then finally the Result verification page. The following paragraphs define the possible usage and the implementation of each of the above mentioned sections in detail.

1. Whole blood activity

To define the whole blood activity make sure the section of Steps which is present on the lower left hand side corner of the toolbox has the text Whole blood activity highlighted (by default the toolbox starts from the whole blood activity page), if not use the arrow keys to get to the whole blood activity page. The input function represents the arterial whole blood activity measured during the course of an experiment. Whole blood activity can be defined either using a simlation tool or by using an experimental data file. Simulation tool uses functions like feng input and gamma3 to simulate the whole blood activity whereas experimental data file shows the activity measured using a blood activity monitor (BAM) or manual samples.

Let us first define the whole blood activity using the simulation tool for which we use the section named Input function.